I experimented with my website layout using the grid in photoshop. To create my grid i used the rulers to measure out each column what i found rather simple. Here are a couple of examples of what i have done.
Using simple colourful boxes to show where i would position everything on my website. For my images i used one column for them what i think is enough. My text that would go next to my images uses up 3 columns so that i don't have to squeeze in all the information. My navigation will only take up one column as i don't think that it will need much room. My header will take up 4 columns and will go over my image and text so that it will be the first thing that you see.
This is what that layout would look with images and text. I think that this layout looks good and is easy to navigate but i think it is slightly boring and could have a bit more going on but not to much more.